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Potential new therapy for Crohn’s, colitis identified

March 19, 2019 dna 0
Researchers have found a compound that may treat inflammatory bowel disease without directly targeting inflammation. The compound tamps down the activity of a gene linked to blood clotting. They discovered that the gene was turned on at sites of intestinal inflammation and damage, and blocking its activity reduces IBD symptoms in mice.
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When a cell’s ‘fingerprint’ can be a weapon against cancer

March 19, 2019 dna 0
A research team has computationally analyzed the expression of marker genes that are associated with a ‘fingerprint’ of cancer cells in thousands of tumors and revealed its therapeutic potential in the fight against cancer. The study shows the types of tumors in which these genes are most active and identifies drugs with the potential to selectively eliminate cells that carry that label.
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Tiny ‘blinkers’ enable simultaneous imaging of multiple biomolecules

March 19, 2019 dna 0
In everyday life, blinking lights can send signals — for example, that a car is going to turn. Now, researchers have engineered tiny ‘blinkers’ that reveal single molecules of RNA or protein inside cells based on the duration and frequency of each flash. The research could allow scientists to see the locations of many different biomolecules in a cell simultaneously, possibly leading to better diagnostics and treatments.