No Image

Life in Antarctica’s ice mirrors human disease

June 14, 2019 dna 0
Mapping tens of thousands of genes from a group of Antarctic fishes called notothenioids, a team of researchers has discovered that the massive amount of genetic change required for life in the Antarctic occurred long before the Antarctic cooled. These genetic changes not only have major implications for understanding the evolution of Antarctica’s unusual animals, but also highlight that some key adaptations used by fishes mirror the genetics of human bone diseases such as osteoporosis.
No Image

Learning from nature’s bounty: New libraries for drug discovery

June 14, 2019 dna 0
Natural products make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. Their size and complexity has made it difficult to emulate on Nature’s success in the laboratory. By completing a complex molecular synthesis of these compounds attached to a unique identifying DNA strand, Chemists have built a rich collection of natural product-like macrocycles that can be mined for new medicines.
No Image

Viruses found to use intricate ‘treadmill’ to move cargo across bacterial cells

June 14, 2019 dna 0
Using advanced technologies to explore the inner workings of bacteria, biologists have provided the first example of cargo within bacteriophage cells transiting along treadmill-like structures. The discovery demonstrates that bacteria have more in common with sophisticated human cells than previously believed.
No Image

Discovery of new genetic causes of male infertility

June 14, 2019 dna 0
The man is implicated in about half of all cases of infertility. Despite the known importance of genetic factors in the non-production of sperm, only about 25% of these cases can be explained currently. Now a study has uncovered new potential genetic causes, and this discovery will help to develop better diagnostic tests for male infertility.