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Humans co-evolved with immune-related diseases — and it’s still happening

November 30, 2019 dna 0
Some of the same mutations allowing humans to fend off deadly infections also make us more prone to certain inflammatory and autoimmune diseases, such as Crohn’s disease. Researchers describe how ancestral origins impact the likelihood that people of African or Eurasian descent might develop immune-related diseases. The authors also share evidence that the human immune system is still evolving.
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What do we know about the gut microbiota in Parkinson’s disease?

November 29, 2019 dna 0
Since the discovery that the gut microbiome may play a role in the development of Parkinson’s disease (PD), this fresh scientific approach has produced varying results. Scientists compare results of current research and provide recommendations to increase the comparability and utility of these studies with a view towards improving patient outcomes.
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Genetics may determine who benefits from broccoli’s effects on kidney health

November 29, 2019 dna 0
Deletion of the gene that codes for an enzyme called GSTM1 increased kidney injury in mice with hypertension and kidney disease, but supplementing the diet with broccoli powder lessened kidney injury in the genetically altered mice. In humans, high consumption of broccoli and other cruciferous vegetables was linked with a lower risk of kidney failure, primarily in individuals lacking GSTM1.
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Researchers link sisters’ paralysis to an ‘extremely rare’ genetic variant

November 29, 2019 dna 0
Following a nearly 25-year search across three continents, parents of a pair of sisters — who as children slowly became paralyzed from the waist down — finally have a diagnosis. Thanks to a chance viewing on French TV of a story about another physically disabled child who regained her mobility after being diagnosed at TGen, the parents of the two sisters contacted TGen, hoping to end their decades-long diagnostic odyssey.