Environmental enrichment can partially correct miswired neurons in the visual pathway, according to new research.
Some of the same mutations allowing humans to fend off deadly infections also make us more prone to certain inflammatory and autoimmune diseases, such as Crohn’s disease. Researchers describe how ancestral origins impact the likelihood that people of African or Eurasian descent might develop immune-related diseases. The authors also share evidence that the human immune system is still evolving.
A new study finds that neurons affected in Parkinson’s disease can shut down without fully dying, allowing them to also switch off neighboring cells. The findings might give scientists a better understanding of how the condition wrecks havoc in the brain, as well as ideas for new treatments.
Since the discovery that the gut microbiome may play a role in the development of Parkinson’s disease (PD), this fresh scientific approach has produced varying results. Scientists compare results of current research and provide recommendations to increase the comparability and utility of these studies with a view towards improving patient outcomes.
Scientists report the discovery of ‘hyperhotspots’ in the human genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome average.
Bacteria associated with Crohn’s disease rely on multiple stress responses to survive, multiply, and tolerate antibiotics within white blood cells called macrophages, according to a new study.
Deletion of the gene that codes for an enzyme called GSTM1 increased kidney injury in mice with hypertension and kidney disease, but supplementing the diet with broccoli powder lessened kidney injury in the genetically altered mice. In humans, high consumption of broccoli and other cruciferous vegetables was linked with a lower risk of kidney failure, primarily in individuals lacking GSTM1.
Following a nearly 25-year search across three continents, parents of a pair of sisters — who as children slowly became paralyzed from the waist down — finally have a diagnosis. Thanks to a chance viewing on French TV of a story about another physically disabled child who regained her mobility after being diagnosed at TGen, the parents of the two sisters contacted TGen, hoping to end their decades-long diagnostic odyssey.