Medicines made from coiled protein fragments could provide a new handle on hard-to-treat diseases like cancer, but they are difficult to design. But a new technique could change that.
Recycled and aged human urine can be used as a fertilizer with low risks of transferring antibiotic resistant DNA to the environment, according to new research.
Researchers say they have identified a previously unknown gene and associated protein (which they have named ‘aggregatin’) which could potentially be suppressed to slow the advance of Alzheimer’s disease.
A research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington’s Disease. Using genetic mouse models, they have discovered that neurons in the striatum, a brain area involved in controlling movement, require the huntingtin gene for regulating the body’s movements, maintaining cell health during aging, and developing functioning connections between cells.
The DNA molecule inside the nucleus of any human cell is more than six feet long. To fit into such a small space, it must fold into precise loops that also govern how genes are turned on or off. New research indicates that ‘jumping genes’ play a surprising role in stabilizing the 3D folding patterns of the DNA molecule inside the cell’s nucleus.
An expert panel has critically reevaluated the scientific evidence for all 17 reported genes linked to long QT syndrome, disputing nine of the genes and revealing only three of the genes to be definitively associated with the most common form of the disease.
Research using heart cells from squirrels, mice and people identifies an evolutionary mechanism critical for heart muscle function.
Even more detailed insights into the cell will be possible in future with the help of a new development: Scientists have succeeded in accelerating a hundred thousand-fold the nuclear magnetic resonance (NMR) method for investigating RNA.
A research team including 245 undergraduates has published an encyclopedia of more than 1,000 genes, including 421 genes whose functions were previously unknown. The research, conducted in fruit flies, should be useful to scientists studying genes involved in sleep, vision, memory and many other processes in humans.
A research team has, for the first time, identified specific regions of chromosome 21, which cause memory and decision-making problems in mice with Down syndrome, a finding that provides valuable new insight into the condition in humans.