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Tiny ‘blinkers’ enable simultaneous imaging of multiple biomolecules

March 23, 2019 dna 0
In everyday life, blinking lights can send signals — for example, that a car is going to turn. Now, researchers have engineered tiny ‘blinkers’ that reveal single molecules of RNA or protein inside cells based on the duration and frequency of each flash. The research could allow scientists to see the locations of many different biomolecules in a cell simultaneously, possibly leading to better diagnostics and treatments.
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Using more-specific ‘genetic scissors’ may avoid problems associated with gene editing

March 23, 2019 dna 0
A new study suggests that there could be a way to bypass barriers to making CRISPR gene-editing treatments a viable option. Researchers found that using more-precise gene-editing technology that induces fewer breaks in DNA may keep stem cells’ natural damage-response pathways under control.
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Study finds cells maintain a complete molecular ‘memory’ of their embryonic origins

March 23, 2019 dna 0
In research that casts cells as curators of their own history, scientists have discovered that adult tissues retain a memory, inscribed on their DNA, of the embryonic cells from which they arose. The discovery led to one even more intriguing — that the memory is fully retrievable: under certain conditions, cells can play the story of their development in reverse to switch on genes that were active in the fetal state.