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New technique ‘prints’ cells to create diverse biological environments

March 28, 2020 dna 0
With the help of photolithography and programmable DNA, researchers have created a new technique that can rapidly ‘print’ two-dimensional arrays of cells and proteins that mimic a wide variety of cellular environments in the body. This technique could help scientists develop a better understanding of the complex cell-to-cell messaging that dictates a cell’s final fate.
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Gene variants may increase susceptibility to accumulate Alzheimer’s protein tau

March 28, 2020 dna 0
The toxic protein tau is a key biological feature in the brains of people with Alzheimer’s disease. Yet the factors that make people susceptible or resistant to tau accumulation are not well-understood. A preliminary study shows that inherited DNA variants may be associated with developing tau deposits in older adults.
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Synthetic biologists redesign the way bacteria ‘talk’ to each other

March 28, 2020 dna 0
Bioengineers have redesigned how harmless E. coli bacteria ”talk” to each other. The new genetic circuit could become a useful new tool for synthetic biologists who, as a field, are looking for ways to better control the bacteria they engineer to perform all sorts of tasks, including drug delivery, bioproduction of valuable compounds, and environmental sensing.
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Novel sepsis treatment enhances bacterial capture by neutrophil ‘traps’

March 28, 2020 dna 0
Researchers have developed a novel treatment for sepsis – one of the leading causes of hospital death – that enhances the body’s bacteria-capturing neutrophil extracellular traps (NETs) so that they more effectively capture infectious bacteria, resist degradation, and improve sepsis outcomes and survival.