A team of biologists has discovered how cells become different from each other during embryogenesis, a finding that offers new insights into genetic activity and has implications for better understanding the onset of disease and birth defects.
A new study sheds new light on how the CD2AP gene may enhance Alzheimer’s disease susceptibility.
Scientists have identified a pair of genes that influence risk for both late-onset and early-onset Alzheimer’s disease.
Three decades of research on Alzheimer’s disease have not produced major treatment advances for patients. Researchers now report new insights that may lead to progress in fighting the devastating disease. They discovered beta amyloid has a specific amino acid that can form a kink, like a kink in a garden hose, creating a harmful molecular zipper and leading to the death of neurons.
Scientists have identified a specific gene they believe could be a key player in the changes in brain structure seen in several psychiatric conditions, such as schizophrenia and autism.
Pluripotent cells can give rise to all cells of the body, a power that researchers are eager to control because it opens the door to regenerative medicine and organ culture for transplants. But pluripotency is still a black box for science, controlled by unknown genetic and epigenetic signals. Researchers have now uncovered one of those epigenetic signals, after a detective quest that started almost a decade ago.
A new study has written the most detailed ‘parts list’ of the human brain to date. This categorization of our brain cell types lays the groundwork to improve our understanding of our own brains and to dramatically change how we treat human brain diseases and disorders.
Slow electons can be used to destroy cancer cells – but how exactly this happens has not been well understood. Now scientists have been able to demonstrate that a previously little-observed effect actually plays a pivotal role: Due to a process called interatomic Coulombic decay, an ion can pass on additional energy to surrounding atoms. This frees a huge number of electrons, with precisely the right amount of energy to cause optimal damage to the DNA of the cancer cells.
Research led by Kyushu University finds that E. coli from cattle share widespread genetic similarities with those that cause food poisoning in humans, indicating that the traits that are harmful to humans may emerge to improve survival in the bovine intestine.
A new computational tool called ProtFus screens scientific literature to validate predictions about the activity of fusion proteins — proteins encoded by the joining of two genes that previously encoded two separate proteins.