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In mice, feeding time influences the liver’s biological clock

April 20, 2019 dna 0
The timing of food intake is a major factor driving the rhythmic expression of most genes in the mouse liver, researchers report. The findings demonstrate that body-wide signals driven by rhythmic food intake significantly contribute to driving rhythms in liver metabolic functions and gene expression independently of the liver and clock.
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Probing the mystery of drug resistance: New hope for leukemia’s toughest cases

April 20, 2019 dna 0
A medical researcher has made it his mission to figure out why leukemia treatments cure some patients but not others. He and his team report progress on two important fronts: They shed light on how leukemia cells become resistant to drugs, and they describe how two drugs used in combination may overcome that resistance, offering new hope to thousands of children and adults with leukemia.
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Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment

April 20, 2019 dna 0
Glioblastoma is one of the most devastating forms of cancer, with few existing treatment options. It is also a leading cause of cancer-related death in children and young adults. Scientists have ‘reverse engineered’ brain cancer stem cells gene by gene, uncovering multiple potential targets for this hard-to-treat cancer.