Brain discovery explains a great mystery of Alzheimer’s, Parkinson’s

One of the great mysteries of neuroscience may finally have an answer: Scientists have identified a potential explanation for the mysterious death of specific brain cells seen in Alzheimer’s, Parkinson’s and other neurodegenerative diseases.
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Lipoproteins behave ‘almost like a tiny Velcro ball’

Setbacks in drug trials aiming to raise HDL have led researchers to reassess the particle’s effects on heart health. A study combining proteomics and mouse genetics may help researchers understand researchers understand the proteins in the particle, how they get there and how they determine HDL function.
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Micro-control of liver metabolism

A new discovery has shed light on small RNAs called microRNAs in the liver that regulate fat and glucose metabolism. Research shows that a molecular anticipation, during fast to re-feed transition, is essential for capping glucose production by the liver. This novel control enables a rapid switch in physiology following food consumption. Besides the therapeutic potential, the findings show that these mechanisms may be associated with metabolic diseases and aging.
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CRISPR/Cas9 therapy can suppress aging, enhance health and extend life span in mice

Researchers have developed a new gene therapy to help decelerate the aging process. The findings highlight a novel CRISPR/Cas9 genome-editing therapy that can suppress the accelerated aging observed in mice with Hutchinson-Gilford progeria syndrome, a rare genetic disorder that also afflicts humans.
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How to block new antibiotic resistance gene

A new antimicrobial-resistance gene, VCC-1, a beta-lactamase gene, has been discovered in benign close relatives of virulent Vibrio cholerae, which causes cholera. Now, a team of Canadian researchers has found a way to block the VCC-1 enzyme, which disables that resistance gene.
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