Scientists havedesigned a device that can induce partial hindlimb regeneration in adult aquatic African clawed frogs (Xenopus laevis) by ‘kick-starting’ tissue repair at the amputation site. Their findings introduce a new model for testing ‘electroceuticals,’ or cell-stimulating therapies.
Millions of couples who have trouble conceiving may get relief from new research. The researchers have developed a high-resolution genetic map showing how men produce sperm cells. Their effort could help address genetically based challenges with male fertility, a major cause of conception problems.
Scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.
Researchers have collected a globally unique KidCMP cohort of children with severe cardiomyopathies from the past 21 years, and characterized them genetically. The researchers discovered that the genetic knowledge had direct implications for predicting the disease course and treatment decisions.
Scientists who treasure hunt for interesting bacterial metabolites using the online tool antiSMASH now have the opportunity to use an antiSMASH database with pre-calculated results of nearly 25,000 bacterial genomes. This database will ease the discovery of antibiotics, pesticides, and anti-cancer drugs.
New research highlights a novel bone anabolic agent that, when injected, intravenously reduces femur fracture healing time by 60 percent without impacting the surrounding healthy tissue.
A new study by Washington State University researchers suggests that a protein called CDK2 plays a critical role in heart damage caused by doxorubicin, a commonly used chemotherapy drug. Published in the Journal of Biological Chemistry, their finding could be used as the basis for future development of treatment strategies and drugs to reduce heart disease risk in cancer survivors, especially those treated in childhood.
Researchers have made an unexpected and vital contribution to an international collaborative effort in Parkinson’s disease research.
A pioneering technique designed to spot differences between immune cells in tumours could speed the development of cancer treatments, research suggests.
Investigators have discovered that template-free Cas9 editing is predictable, and they have developed a machine learning model that can predict insertions and deletions with high accuracy.