Researchers discover the enzyme SPRK1’s role in reorganizing the paternal genome during the first moments of fertilization — a finding that might help explain infertility cases of unknown cause.
Scientists have discovered a possible link between Parkinson’s disease and a gene impacted by a neurotoxin found in blue-green algae.
Early on in each cell, a critical protein known as FoxA2 simultaneously binds to both the chromosomal proteins and the DNA, opening the flood gates for gene activation, according to a new study. The discovery helps untangle mysteries of how embryonic stem cells develop into organs.
With the help of photolithography and programmable DNA, researchers have created a new technique that can rapidly ‘print’ two-dimensional arrays of cells and proteins that mimic a wide variety of cellular environments in the body. This technique could help scientists develop a better understanding of the complex cell-to-cell messaging that dictates a cell’s final fate.
Genetics researchers say a new approach could benefit all sorts of serious health conditions, and they’re urging scientists to quickly pluck ‘low hanging fruit’ for the benefit of patients.
Researchers discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection of Alzheimer’s disease. The work could lead to the development of a blood test to identify individuals who will develop the disease years before they show symptoms.
Researchers used iPS cells to reconstructed the human ‘segmentation clock,’ a key point in early embryonic development that determines how the body gets segmented. The ‘segmentation clock’ is a genetic oscillator that controls and guides the emergence of ‘somites,’ distinct collections of cells that contribute to the formation of the vertebrae and ribs. Segmentation clock genes a have been studied extensively in many animals, except humans.
Scientists traced how the two major human migrations recorded in Holocene Europe — the northwestward movement of Anatolian farmer populations during the Neolithic and the westward movement of Yamnaya steppe peoples during the Bronze Age — unfolded.
A new study offers clues to why autism spectrum disorder (ASD) is more common in boys than in girls. National Institutes of Health scientists found that a single amino acid change in the NLGN4 gene, which has been linked to autism symptoms, may drive this difference in some cases.