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A light-activated remote control for cells

April 17, 2019 dna 0
What if doctors had a remote control that they could use to steer a patient’s own cells to a wound to speed up the healing process? Although such a device is still far from reality, researchers have taken an important first step: They used near-infrared light and an injected DNA nanodevice to guide stem cells to an injury, which helped muscle tissue regrow in mice.
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How Enterococcus faecalis bacteria causes antibiotic resistant infection

April 17, 2019 dna 0
A new study describes how bacteria adapted to the modern hospital environment and repeatedly cause antibiotic-resistant bloodstream infections. This study examined one of the first sustained hospital outbreaks of a multidrug-resistant bacterium, Enterococcus faecalis, which occurred from the early through the mid-1980s, causing over 60 outbreak strains.
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Factors behind embryonic stem cell state

April 17, 2019 dna 0
An international collaboration has found for the first time that two new epigenetic regulators, TAF5L and TAF6L, maintain self-renewal of embryonic stem cells. The scientists also found that these proteins activate c-Myc (a well-known cancer gene), and its regulatory network. This is the first time scientists have been able to show what these regulators do and how they control gene expression.
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Gene therapy restores immunity in infants with rare immunodeficiency disease

April 17, 2019 dna 0
A small clinical trial has shown that gene therapy can safely correct the immune systems of infants newly diagnosed with a rare, life-threatening inherited disorder in which infection-fighting immune cells don’t develop or function normally. Eight infants with the disorder, called X-linked severe combined immunodeficiency (X-SCID), received experimental gene therapy. They experienced substantial improvements in immune system function and normal growth up to two years after treatment.
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Direct-to-Consumer Genetic Testing’s Red Herring: “Genetic Ancestry” and Personalized Medicine.

April 17, 2019 dna 0
Related Articles

Direct-to-Consumer Genetic Testing’s Red Herring: “Genetic Ancestry” and Personalized Medicine.

Front Med (Lausanne). 2019;6:48

Authors: Blell M, Hunter MA

Abstract
The growth in the direct-to-consumer genetic testing industry poses a number of challenges for healthcare practice, among a number of other areas of concern. Several companies providing this service send their customers reports including information variously referred to as genetic ethnicity, genetic heritage, biogeographic ancestry, and genetic ancestry. In this article, we argue that such information should not be used in healthcare consultations or to assess health risks. Far from representing a move toward personalized medicine, use of this information poses risks both to patients as individuals and to racialized ethnic groups because of the way it misrepresents human genetic diversity.

PMID: 30984759 [PubMed]