Researchers have found a way to sequence a large portion of the Y chromosome in the fruit fly Drosophila melanogaster — the most that the Y chromosome has been assembled in fruit flies. The research provides new insights into the processes that shape the Y chromosome, adding to the evidence that, far from a genetic wasteland, Y chromosomes are highly dynamic and have mechanisms to acquire and maintain genes.
Researchers have created a basic framework of how cancer cells adapt when their attempts to metastasize are blocked by drugs or the body’s immune system. Understanding the cells’ strategies could someday help scientists design therapies that keep them in check.
For some of us, they carry the bright blue of our grandfather’s eyes. For others they result in the characteristic cleft chin or the familial tendency toward color blindness. But in some families, the genetic mutations handed down from generation to generation aren’t as benign. And for one family in particular, the mutation results in early-onset Alzheimer’s disease.
Setbacks in drug trials aiming to raise HDL have led researchers to reassess the particle’s effects on heart health. A study combining proteomics and mouse genetics may help researchers understand researchers understand the proteins in the particle, how they get there and how they determine HDL function.
One of the great mysteries of neuroscience may finally have an answer: Scientists have identified a potential explanation for the mysterious death of specific brain cells seen in Alzheimer’s, Parkinson’s and other neurodegenerative diseases.
According to a new study, birch pollen allergen immunotherapy modifies the gene expression and microbiome profile of the nasal epithelium to correspond to those of healthy controls.