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Researchers wirelessly hack ‘boss’ gene, a step toward reprogramming the human genome

July 26, 2019 dna 0
A new study describes how researchers wirelessly controlled FGFR1 — a gene that plays a key role in how humans grow from embryos to adults — in lab-grown brain tissue. The ability to manipulate the gene, the study’s authors say, could lead to new cancer treatments, and ways to prevent and treat mental disorders such as schizophrenia.
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Overstuffed cancer cells may have an Achilles’ heel

July 26, 2019 dna 0
In a study using yeast cells and data from cancer cell lines, scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry genetic material. The vulnerability, they say, is rooted in a common feature among cancer cells — their high intracellular protein concentrations — that make them appear bloated and overstuffed, and which could be used as possible new targets for cancer treatments.
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Alzheimer’s protein is likely held together with many weak chemical interactions

July 26, 2019 dna 0
The chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. Chemists modeled the building blocks of the protein structure that causes Alzheimer’s disease, amyloid beta sheets. Their calculations revealed that some atoms too far apart to bond were still in each other’s ‘electron neighborhoods.’